Yes, it is provided you use a condom and lots of lube.

Anal sex, unlike vaginal sex, requires a lot of lubrication as the anus is not naturally lubricated. Once lubricated, you should relax since the muscles around the rectum is stiff. Fast movements in anal sex could lead to small tears. Hence it’s advisable to move slowly. The risk of getting STIs/STDs is high during anal sex, but using a condom is a sure way to stay protected. Also, make sure to maintain proper hygiene. If, during the act, the condom tears or cuts, make sure you visit the doctor and get yourself checked. Keep in mind to use a new condom when you’re switching from anal to vaginal sex. Stay safe, play safe!